Complement Cascade RoundUp

So it’s been a few days since I last posted (whoops), but I’ve been busy writing up what we have for the sea star transcriptome and in particular what complement cascade genes we have.  Echinoderms were already described as having two proteins involved in the complement cascade: C3 and C2/Bf, however we found two more which were significantly deferentially expressed: Ficolin-2 and Properdin.  Both of these are proteins involved in alternate activation of the complement cascade system.  Looks like the infected stars are definitely responding to something though we’re still working at getting the full picture of how they’re responding and to what.

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